Plump · Learn More About Toxins
Botox & Dysport, plus the other four
All six FDA-approved neurotoxins, side by side — onset, longevity, and who each one suits best.
| Botox®onabotulinumtoxinAHouse standard | Dysport®abobotulinumtoxinAHouse standard | Xeomin®incobotulinumtoxinA | Jeuveau®prabotulinumtoxinA | Letybo®letibotulinumtoxinA | Daxxify®daxibotulinumtoxinALongest-lasting | |
|---|---|---|---|---|---|---|
| Onset | 3–5 days | 2–3 days | 3–5 days | 3–5 days | Comparable to Botox | 2–3 days |
| Duration | 3–4 months | 3–4 months | 3–4 months | 3–4 months | 3–4 months | 3–6 months |
| Cadence | Every 3–4 months | Every 3–4 months | Every 3–4 months | Every 3–4 months | Every 3–4 months | Every 3–6 months |
| Clinical distinction | The original and most-studied option — predictable, conservatively dosed. | Diffuses slightly more — often preferred for broad areas like the forehead. | A naked toxin — no complexing proteins. A good choice if other brands have felt less effective over time. | Developed specifically for aesthetics. Onset and duration comparable to Botox. | The newest FDA-approved option — a clean precision profile for frown lines. | The longest-lasting option — a good fit if other brands fade before your next visit. |
| Downtime | None | None | None | None | None | None |
| Pairs well with | Fillers · Sculptra · Skinvive | Fillers · Sculptra · Skinvive | Fillers · Sculptra · Skinvive | Fillers · Sculptra · Skinvive | Fillers · Sculptra · Skinvive | Fillers · Sculptra · Skinvive |
Botox®
onabotulinumtoxinA
House standardOnset3–5 days
Duration3–4 months
CadenceEvery 3–4 months
Clinical distinctionThe original and most-studied option — predictable, conservatively dosed.
DowntimeNone
Pairs well withFillers · Sculptra · Skinvive
Dysport®
abobotulinumtoxinA
House standardOnset2–3 days
Duration3–4 months
CadenceEvery 3–4 months
Clinical distinctionDiffuses slightly more — often preferred for broad areas like the forehead.
DowntimeNone
Pairs well withFillers · Sculptra · Skinvive
Xeomin®
incobotulinumtoxinA
Onset3–5 days
Duration3–4 months
CadenceEvery 3–4 months
Clinical distinctionA naked toxin — no complexing proteins. A good choice if other brands have felt less effective over time.
DowntimeNone
Pairs well withFillers · Sculptra · Skinvive
Jeuveau®
prabotulinumtoxinA
Onset3–5 days
Duration3–4 months
CadenceEvery 3–4 months
Clinical distinctionDeveloped specifically for aesthetics. Onset and duration comparable to Botox.
DowntimeNone
Pairs well withFillers · Sculptra · Skinvive
Letybo®
letibotulinumtoxinA
OnsetComparable to Botox
Duration3–4 months
CadenceEvery 3–4 months
Clinical distinctionThe newest FDA-approved option — a clean precision profile for frown lines.
DowntimeNone
Pairs well withFillers · Sculptra · Skinvive
Daxxify®
daxibotulinumtoxinA
Longest-lastingOnset2–3 days
Duration3–6 months
CadenceEvery 3–6 months
Clinical distinctionThe longest-lasting option — a good fit if other brands fade before your next visit.
DowntimeNone
Pairs well withFillers · Sculptra · Skinvive
Not every toxin shown here is available at Plump — our house standards are Botox Cosmetic and Dysport, with select alternatives by request. Text us to learn more → Duration varies by individual — your injector will be direct about what to expect. For reference only; not medical advice.